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Jack A Roth Selected Research

oncrasin-266

10/2014Prodrug oncrasin-266 improves the stability, pharmacokinetics, and safety of NSC-743380.

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Jack A Roth Research Topics

Disease

147Neoplasms (Cancer)
11/2022 - 01/2002
88Lung Neoplasms (Lung Cancer)
01/2022 - 02/2002
83Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2022 - 03/2002
19Neoplasm Metastasis (Metastasis)
01/2021 - 01/2002
18Esophageal Neoplasms (Esophageal Cancer)
01/2021 - 01/2002
16Adenocarcinoma
11/2021 - 01/2003
11Carcinoma (Carcinomatosis)
01/2020 - 12/2003
10Melanoma (Melanoma, Malignant)
01/2010 - 04/2002
9Carcinogenesis
01/2021 - 02/2003
6Malignant Mesothelioma
01/2022 - 09/2007
6Pathologic Complete Response
01/2021 - 12/2005
6Infections
06/2017 - 03/2002
6Breast Neoplasms (Breast Cancer)
08/2011 - 11/2002
5Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 11/2003
5Pneumonia (Pneumonitis)
01/2021 - 08/2010
5Adenocarcinoma of Lung
10/2020 - 09/2005
5Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2020 - 11/2003
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2008 - 11/2003
3Hemorrhage
01/2021 - 12/2017
3Leukemia
11/2017 - 01/2015
3Inflammation (Inflammations)
09/2014 - 12/2004
3Ataxia Telangiectasia (Louis Bar Syndrome)
08/2010 - 11/2003
3Prostatic Neoplasms (Prostate Cancer)
03/2005 - 03/2002
2Metaplasia
01/2021 - 02/2003
2Esophagitis
01/2016 - 08/2010
2Sarcoma (Soft Tissue Sarcoma)
05/2011 - 09/2007

Drug/Important Bio-Agent (IBA)

29Proteins (Proteins, Gene)FDA Link
01/2020 - 03/2002
20Biomarkers (Surrogate Marker)IBA
01/2019 - 08/2002
18DNA (Deoxyribonucleic Acid)IBA
01/2020 - 12/2002
10CholesterolIBA
02/2016 - 03/2003
9eIF-2 Kinase (eIF 2 Kinase)IBA
01/2020 - 04/2002
8MicroRNAs (MicroRNA)IBA
01/2019 - 08/2009
81,2- dioleoyloxy- 3- (trimethylammonium)propaneIBA
02/2016 - 03/2003
7CytokinesIBA
01/2020 - 08/2003
7Biological ProductsIBA
11/2018 - 03/2005
7ErbB Receptors (EGF Receptor)IBA
11/2016 - 03/2003
6Messenger RNA (mRNA)IBA
11/2016 - 08/2003
6Pharmaceutical PreparationsIBA
11/2016 - 11/2002
5AZD 6244IBA
01/2022 - 11/2009
5Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2022 - 11/2009
5Phosphotransferases (Kinase)IBA
10/2020 - 12/2002
5Therapeutic UsesIBA
01/2017 - 07/2002
5Cisplatin (Platino)FDA LinkGeneric
08/2010 - 06/2004
5CaspasesIBA
07/2007 - 06/2002
4Immune Checkpoint InhibitorsIBA
11/2022 - 01/2019
4AntibodiesIBA
01/2022 - 03/2003
4InterleukinsIBA
01/2022 - 03/2005
4AntigensIBA
01/2019 - 03/2003
41- ((3- chlorophenyl)methyl)- 1H- indole- 3- carbinolIBA
11/2017 - 05/2012
4Antineoplastic Agents (Antineoplastics)IBA
01/2015 - 11/2003
4Small Interfering RNA (siRNA)IBA
09/2012 - 11/2007
4interleukin-24 (ST16)IBA
05/2005 - 08/2003
3NivolumabIBA
11/2022 - 01/2019
3Oxygen (Dioxygen)IBA
09/2021 - 01/2018
3Transcription Factors (Transcription Factor)IBA
01/2021 - 09/2007
3Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
10/2020 - 02/2009
3EnzymesIBA
01/2019 - 01/2012
3Auranofin (Ridaura)FDA Link
01/2019 - 01/2016
3Erlotinib Hydrochloride (CP 358,774)FDA Link
11/2016 - 09/2014
3MK 2206IBA
09/2013 - 11/2010
3Indicators and Reagents (Reagents)IBA
06/2013 - 09/2006
3Telomerase (Telomerase Reverse Transcriptase)IBA
09/2007 - 07/2002
3Liposomes (Liposome)IBA
11/2004 - 03/2003
3Paclitaxel (Taxol)FDA LinkGeneric
09/2004 - 11/2002
2IpilimumabIBA
11/2022 - 01/2021
2pembrolizumabIBA
01/2022 - 01/2019
2Lysine (L-Lysine)FDA Link
01/2021 - 04/2002
2Histones (Histone)IBA
01/2021 - 01/2012
2MethyltransferasesIBA
01/2021 - 01/2012
2ParaffinIBA
10/2020 - 01/2018
2Formaldehyde (Formol)FDA Link
10/2020 - 01/2018
2Cell-Free Nucleic AcidsIBA
01/2020 - 01/2018
2Glutathione (Reduced Glutathione)IBA
01/2019 - 01/2019
2Tyrosine Kinase InhibitorsIBA
01/2019 - 01/2015
2HLA Antigens (Human Leukocyte Antigens)IBA
01/2019 - 01/2017
2Thioredoxin-Disulfide ReductaseIBA
01/2019 - 01/2019
2Peptides (Polypeptides)IBA
01/2017 - 06/2007
2C-Reactive ProteinIBA
11/2016 - 01/2016
2Insulin-Like PeptidesIBA
12/2013 - 01/2013
2Green Fluorescent ProteinsIBA
09/2012 - 09/2007
2PlatinumIBA
01/2012 - 05/2011
2Cyclin B1IBA
01/2012 - 12/2010
2Histidine (L-Histidine)FDA Link
12/2011 - 11/2007
2LipidsIBA
01/2011 - 08/2010

Therapy/Procedure

75Therapeutics
12/2022 - 01/2002
30Radiotherapy
10/2021 - 01/2002
28Drug Therapy (Chemotherapy)
11/2022 - 01/2002
14Chemoradiotherapy
09/2013 - 09/2003
13Esophagectomy
12/2022 - 01/2002
11Immunotherapy
01/2022 - 02/2002
10Neoadjuvant Therapy
11/2021 - 09/2010
8Induction Chemotherapy
01/2019 - 09/2003
5Metastasectomy
09/2019 - 09/2009
4Pneumonectomy (Lung Volume Reduction)
01/2022 - 03/2004
4Length of Stay
01/2018 - 01/2002
3Aftercare (After-Treatment)
01/2020 - 10/2017
3Operative Surgical Procedures
02/2009 - 12/2003
3Intravenous Administration
04/2008 - 03/2003
2Adjuvant Chemotherapy
01/2019 - 01/2012
2Thoracotomy
03/2018 - 01/2018